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Health & Wellness Scientific Expertise and Resources
The Science Behind the Nutrition
With ADM, you have a spectrum of nutrition expertise spanning everyday human and animal nutrition. You also have functional health capabilities—all an extension of your own resources. Along with cutting-edge science, the health & wellness team at ADM possesses the technical ingenuity and regulatory expertise you need to create successful products.
You will benefit from our global academia, agency and organization engagement, as well as our broad regulatory expertise, including:
- USDA Foods/School Nutrition
- USDA Food Assistance
- International Development
Scientific Capabilities
We take a global view when it comes to our nutrition science engagement, providing leadership to professional organizations. We are supporting global, trans-disciplinary research initiatives and advocacy. ADM’s health & wellness team promotes cross-organization integration of nutrition initiatives, as well as rigorously supporting nutrition research.
Our broad research development expertise includes:
- Epidemiology
- Pre-clinical models
- Human clinical
Clinical Trials
Clinical trials for specific ADM health & wellness products are published in peer-reviewed journals. Our microbiome trials have been published in 59 industry publications.
Our research capabilities and clinical trials:
- Pre-clinical evaluation, including in vitro, cell cultures, and C.elegans models
- Omics analysis, including genomics and metabolomics
- Microbiome analysis
- Strain development, including pilot, scale-up and stability
Scientific Publications
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- Probiotic and cranberry supplementation for preventing recurrent uncomplicated urinary tract infections in premenopausal women: a controlled pilot study; Koradia, 2019
- Safety and Immunomodulatory Effects of Three Probiotic Strains Isolated from the Feces of Breast-Fed Infants in Healthy Adults: SETOPROB Study; Plaza-Diaz, 2013
- Pyrosequencing Analysis Reveals Changes in Intestinal Microbiota of Healthy Adults Who Received a Daily Dose of Immunomodulatory Probiotic Strains; Plaza-Diaz, 2015
- Bifidobacterium longum subsp infantis CECT7210-supplemented formula reduces diarrhea in healthy infants: a randomized controlled trial; Escribano, 2018
- Isolation, identification and characterisation of three novel probiotic strains (Lactobacillus paracasei CNCM I-4034, Bifidobacterium breve CNCM I-4035 and Lactobacillus rhamnosus CNCM I-4036) from the faeces of exclusively breast-fed infants; Muñoz-Quezada, 2013
- Competitive inhibition of three novel bacteria isolated from faeces of breast milk-fed infants against selected enteropathogens; Muñoz-Quezada, 2013
- Novel Probiotic Bifidobacterium longum subsp. infantis CECT 7210 Strain Active against Rotavirus Infections; Muñoz, 2011
- Identification of a Peptide Produced by Bifidobacterium longum CECT 7210 with Antirotaviral Activity; Chenoll, 2016
- Evaluation of the Probiotic Strain Bifidobacterium longum subsp. infantis CECT 7210 capacities to Improve Health Status and Fight Digestive Pathogens in a Piglet Model; Barba-Vidal, 2017
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- A randomized placebo-controlled clinical trial of a multi-strain probiotic formulation (Bio-Kult®) in the management of diarrhea-predominant irritable bowel syndrome; Ishaque, 2018
- The Effectiveness of Synbiotics in Preventing Antibiotic-Associated Diarrhea in Children: A Double-Blind Randomized Clinical Trial; Goli, 2019
- Double-blind, randomised, placebo-controlled intervention trial to evaluate the effects of Bifidobacterium longum CECT 7347 in children with newly diagnosed coeliac disease; Olivares, 2014
- Pilot study on non-celiac gluten sensitivity: effects of Bifidobacterium longum ES1 co-administered with a gluten-free diet; Di Pierro, 2020
- Bifidobacteria Inhibit the Inflammatory Response Induced by Gliadins in Intestinal Epithelial Cells via modifications of Toxic Peptide Generation During Digestion; Laparra and Sanz, 2010
- Bifidobacterium strains suppress in vitro the pro-inflammatory milieu triggered by the large intestinal microbiota of coeliac patients; Medina, 2008
- Influence of Bifidobacterium longum CECT 7347 and gliadin peptides on intestinal epithelial cell proteome; Olivares, 2011
- Modulation of phenotypic and functional maturation of dendritic cells by intestinal bacteria and gliadin: relevance for celiac disease; De Palma, 2012
- Bifidobacterium longum CECT 7347 Modulates Immune Responses in a Gliadin-Induced Enteropathy Animal Model; Laparra, 2012
- Oral administration of Bifidobacterium longum CECT 7347 modulates jejunal proteome in an in vivo gliadin-induced enteropathy animal model; Olivares, 2012
- Oral administration of Bifidobacterium longum CECT 7347 ameliorates gliadin-induced alterations in liver iron mobilization; Laparra, 2013
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- The effects of a multispecies probiotic supplement on inflammatory markers and episodic and chronic migraine characteristics: A randomized double-blind controlled trial; Martami, 2019
- Probiotic Bacillus subtilis Protects against α-Synuclein Aggregation in C. elegans; Goya, 2020
- Probiotics reduce anxiety-related behavior in zebrafish; Valcarce, 2020
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- The effect of probiotics in prevention of necrotising enterocolitis in preterm neonates in comparison with control group; Amini, 2017
- A Multicenter, Prospective, Randomized Controlled Trial to Evaluate the Additional Benefit of a Multistrain Synbiotic (Prodefen®) in the Clinical Management of Acute Viral Diarrhea in Children; Garcia-Menor, 2016
- Synbiotic in the management of infantile colic: a randomised controlled trial; Kianifar, 2014
- Effect of a New Synbiotic Mixture on Atopic Dermatitis in Children: a Randomized-Controlled Trial; Farid, 2011
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- Effects of daily consumption of the probiotic Bifidobacterium animalis subsp. lactis CECT 8145 on anthropometric adiposity biomarkers in abdominally obese subjects: a randomized controlled trial; Pedret, 2019
- Effects of Bifidobacterium animalis subsp. lactis (BPL1) Supplementation in Children and Adolescents with Prader–Willi Syndrome: A Randomized Crossover Trial; Amat-Bou, 2020
- Lipoteichoic acid from Bifidobacterium animalis subsp. lactis BPL1: a novel postbiotic that reduces fat deposition via IGF-1 pathway; Balaguer, 2021
- Probiotic Strain Bifidobacterium animalis subsp. lactis CECT 8145 Reduces Fat Content and Modulates Lipid Metabolism and Antioxidant Response in Caenorhabditis elegans; Martorell; 2016
- Heat-killed Bifidobacterium animalis subsp. lactis CECT 8145 increases lean mass and ameliorates metabolic syndrome in cafeteria-fed obese rats; Caimari, 2017
- An Infant Milk Formula Supplemented with Heat-Treated Probiotic Bifidobacterium animalis subsp. lactis CECT 8145, Reduces Fat Deposition in C. elegans and Augments Acetate and Lactate in a Fermented Infant Slurry; Silva, 2020
- Anti-obesity properties of the strain Bifidobacterium animalis subsp. lactis CECT 8145 in Zücker fatty rats; Lopez-Carreras, 2018
- Effects of Lactobacillus paracasei CNCM I-4034, Bifidobacterium breve CNCM I-4035 and Lactobacillus rhamnosus CNCM I-4036 on Hepatic Steatosis in Zucker Rats; Plaza-Diaz, 2014
- Adamdec1, Ednrb and Ptgs1/Cox1, inflammation genes upregulated in the intestinal mucosa of obese rats, are downregulated by three probiotic strains; Plaza-Diaz, 2017
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- Effect of oral administration of a mixture of probiotic strains on SCORAD index and use of topical steroids in young patients with moderate atopic dermatitis a randomized clinical trial; Navarro-Lopez, 2018
- Efficacy and Safety of Oral Administration of a Mixture of Probiotic Strains in Patients with Psoriasis: A Randomized Controlled Clinical Trial; Navarro-Lopez, 2019
- Gut microbial composition in patients with psoriasis; Codoñer, 2018
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- Probiotic administration improves sperm quality in asthenozoospermic human donors; Valcarce, 2016
- Diet Supplemented with Antioxidant and Anti-Inflammatory Probiotics Improves Sperm Quality after Only One Spermatogenic Cycle in Zebrafish Model; Valcarce, 2019
- Long Exposure to a Diet Supplemented with Antioxidant and Anti-Inflammatory Probiotics Improves Sperm Quality and Progeny Survival in the Zebrafish Model; Valcarce, 2019
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