Peer-Reviewed Journal Animals Publishes ADM's Clinical Trial Using PRIOME® Metabolic Health

As demand for functional pet supplements rises, ADM's clinical study investigating the effects of PRIOME® Metabolic Health (PRIOME® MH) (Bifidobacterium animalis subsp. lactis CECT 8145), in both probiotic and heat-treated postbiotic form in adult dogs, has been published by the prestigious scientific journal, Animals. This publication adds another peer-reviewed canine clinical study to ADM's postbiotic evidence base and differentiates PRIOME® MH within ADM's growing pet biotics portfolio.

Metabolic health is a major determinant of longevity and quality of life. In dogs, it encompasses factors such as weight management, blood glucose regulation, and hormonal balance. Although healthy dogs typically regulate blood sugar well, repeated glucose spikes—particularly in overweight or aging animals—can contribute to insulin resistance and other metabolic challenges.

Led by Dr. Sophie Nixon, Head of Clinical Research for Pet and Animal Wellbeing, this clinical trial has demonstrated the potential role of PRIOME® MH postbiotic to support canine metabolic health. The randomized, double-blind, placebo-controlled clinical study was conducted in 45 healthy adult dogs, evaluating the impact of daily probiotic or postbiotic supplementation on markers of metabolic health during periods of induced weight gain and weight loss. During the weight-loss phase of the trial, dogs receiving PRIOME® MH demonstrated a significant reduction in postprandial blood glucose compared with dogs given placebo.

This trial strengthens the growing evidence for postbiotics in companion animal research, driving innovation in functional nutrition. These findings significantly advance the industry's understanding of postbiotic applications for canine metabolic health – a health area that historically has been underserved by biotic ingredients.

ADM PRIOME Metabolic Health

The full text of the study can be read in Animals here. Learn more about ADM's extensive portfolio of science-backed microbiome solutions for pets here.

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